MHC class II

The expression of MHC class II on MSC , however , could deter their use in repair medicine , since these molecules could stimulate an allogeneic host response .

然而由于其表达组织相容性抗原-II（MHC-II），这些分子可刺激同种异体抗宿主反应，所以限制了MSC在修复医学中的应用。

Suppression of MHC Class II Molecules by Antisense RNA of MHC Class II Transactivator

CIITA反义RNA抑制MHcII类分子表达

Inducible Expression of MHC Class II Antigens on Chondrocytes and Their Rejection in Allogeneic Grafting

MHcII类抗原的诱导性表达和同种异体软骨细胞移植的免疫排斥

It concludes that MAGE , 322,36 was identified as a MHC class II restricted epitope .

从小鼠MAGE-3抗原中筛选出MHcII类分子限制性多肽表位MAGE-322-36。

MHC Class II Transactivator ( CIITA ) Regulates the Expression of HLA Molecules in Tumor Cells

MHcII类反式激活蛋白调控肿瘤细胞HLA分子的表达

Moreover , MSC are poor antigen-presenting cells and do not express MHC class II or co-stimulatory molecules .

而且，MSC是弱的抗原提呈细胞，不表达MHCⅡ类分子或共刺激分子。

Results : IFN - γ was able to increase the expression of MHC class II by gastric epithelial cells , and subsequently enhance the binding of H. pylori .

结果：IFNγ可诱导胃上皮细胞表达MHCⅡ类分子，进而增加Hp的黏附。

Allo responses could be evolved , however , when the chondrocytes began to express the MHC class II antigens after the treatment with swine IFN γ .

经IFNγ诱导后，软骨细胞表达MHcII类抗原，能明显地刺激淋巴细胞增殖。

DC maturation is characterized by profound changes in MHC class II distribution , antigen-processing capacity , and expression of costimulatory molecules , and by a marked rearrangement of adhesion molecules that is likely to allow DC migration to lymphoid organs .

树突状细胞的成熟以MHCⅡ分布，抗原呈递能力？共刺激分子的表达等复杂变化和粘附分子重新分布为主要特征。

Objective : Eosinophils express MHC class II molecules and costimulatory molecules , and function as antigen-presenting cells ( APCs ) to stimulate the proliferation of antigen ( Ag ) - specific CD4 + T lymphocytes both in vitro and in vivo .

目的：嗜酸性粒细胞（EOS）可以表达MHC-Ⅱ类分子和协同刺激分子，在体内和体外实验中证明其都能作为抗原递呈细胞（APC）刺激抗原（Ag）特异性CD4~+T淋巴细胞增殖。

Only the dendritic cells generated by the first step are actually immature , with strong immature dendritic cell features such as active endocytosis , the same expression of monocyte marker CD14 , and much of the MHC class II still lies within intracellular compartments ( MIIC ) .

仅经第一阶段培养的细胞主要为未成熟树突状细胞，仍然表达单核细胞的表面标志CD14，具有活跃的内化活动，其MHC-II分子主要分布在胞内的MIIC器室；

The present study aimed to investigate dynamic changes in TAM major histocompatibility complex ( MHC ) class II expression levels and to assess the effects of these changes on tumor progression .

本研究通过小鼠肝癌模型重点探讨主要组织相容性复合体（MHC）II类分子在TAMs中表达水平的动态变化，并评估这些变化对肿瘤进展的影响。

Mature DC express high levels of major histocompatibility complex ( MHC ) class II and co-stimulatory molecules , such as CD40 , CD80 and CD86 , and thus provide signals required for T-cell activation .

被激活的成熟树突细胞表达高水平的主要组织相容性复合物（MHC）Ⅱ类分子和共刺激分子（co-stimulatorymolecules），例如CD40、CD80和CD86，为激活T细胞提供信号。

IFN-Y is also a potent inducer of MHC class I and II antigens and other cell surface antigens , which increases the antigen-presenting capacity of cells .

可以诱导MHCⅠ类和Ⅱ类抗原及其他细胞表面抗原的表达，从而活化抗原递呈细胞的功能；

A number of MHC class I and class II restricted T-cell epitopes have been described for the MAGE-3 tumor antigen , including 12 MHC class I restricted epitopes and 8 MHC class II restricted epitopes .

MAGE-3肿瘤抗原分子内现已确定12个MHC-Ⅰ类分子限制性表位和8个MHC-Ⅱ类分子限制性表位。

The transfectants and parent B16 cells were treated with 100U / ml of IFN - γ for 36 h before being subjected to experimental metastasis assay . The expression of MHC class I and class II molecules on the cells was analysed by flow cytometry .

亲本B16细胞和基因转导细胞（B16-B7-1和B16-neo）经100U/mlIFN-γ预处理36小时后进行实验性肺转移试验，同时流式细胞分析细胞表面MHCⅠ类和Ⅱ类分子的表达。

Major histocompatibility complex ( MHC ) class II-associated invariant ( Ii ) chain plays a key role in controlling MHC class II function in antigen presentation .

哺乳动物MHC（主要组织相容性复合物）II结合的恒定链在抗原呈递过程中对MHcII的功能调控起着重要的作用。